Anticonvulsant Hypersensitivity Syndrome Associated with Carbamazepine Induced Toxic Epidermal Necrolysis

A Rare Case Report in an Epileptic Child

Abstract

Reporting the case of a seven-year-old boy with complaints of painful exfoliation and blistering of skin involving around 40% of body’s surface area alongwith high grade fever (102 F). Detailed history revealed that he was started on tablet Carbamazepine a month ago for Epilepsy, which was well tolerated for the first two weeks, however after the dose was increased, cutaneous and systemic symptoms began to appear. There are very few case reports of Toxic Epidermal Necrolysis in paediatric population related to the use of Carbamazepine. Hence, importance of cautious use and prompt recognition of side effects must be realized in children.