Gender-Based Frequency and Associated Disability of Rheumatoid Arthritis: A Cross-Sectional Study
Abstract
Objective: To determine the frequency and associated disability of rheumatoid arthritis in male and female patients
Methodology: This was a cross sectional survey conducted at the National Institute of Rehabilitation Science, Pakistan Institute of Medical Science and Pakistan Railways Hospital for one year from February 2019 to February 2020. Study includes diagnosed cases of both genders with ages between 30 to 60 years and fulfilling the 1987 American College of Rheumatology (ACR) criteria. Patients with disabilities due to other reasons were excluded. Sample size of the study was calculated to be 143 using Epi-tool. Sampling technique was non-probability purposive sampling technique. For this study WHODAS-2.0 screening tool was used.
Results: Out of 143 patients, 52 (36.4%) were males and 91(63.6%) were females. The mean age of both males and females was 43.41 ± 8.605 SD. We found that 18 (34.6%) male patients presented with mild disability. While in females, 54 (59.3%), 32 (35.16%), 5 (5.49%), and 0 (0%) patients out of 91, reported with mild, moderate, severe, and extreme disabilities respectively.
Conclusion: RA is more prevalent in females than in males with the majority of the patients reporting mild disability and more female patients disabled than men.
References
Almazrou S, Aljohani H, Aljbreen M, Alqahtani M, Alageel S. Assessment of disability and medication adherence In patients with Rheumatoid Arthritis (RA). J Appl Med Sci. 2016;5:33-42.
Kurowska-Stolarska, M. and S. Alivernini. Synovial tissue macrophages in joint homeostasis, rheumatoid arthritis and disease remission. Nat Rev Rheumatol. 2022;18:384- 397.
Ostrowska M, Maœliñski W, Prochorec-Sobieszek M, Nieciecki M, Sudo³-Szopiñska1 A. Cartilage and bone damage in rheumatoid arthritis. Reumatologia. 2018;56(2):111-120. doi: 10.5114/reum.2018.75523.
Khalil Z, Salim B, Nasim A, Malik S. Patients’ knowledge on Rheumatoid Arthritis—A study at a tertiary care hospital. J Pak Med Assoc. 2017;67(2):256-60.
Handa R, Rao U, Lewis JF, Rambhad G, Shiff S, Ghia CJ. Literature review of rheumatoid arthritis in India. Int J Rheum Dis. 2016;9(5):440-51. doi: 10.1111/1756- 185X.12621.
Ashraf A, Iqbal MN, Iqbal I, Yunus F-u-N, Alam S, Muhammad A, et al. Incidence of Rheumatoid Arthritis in District Narowal, Pakistan. PSM Biol Res. 2016; 1(2):49- 52.
Zyrianova, Y. Rheumatoid arthritis: a historical and biopsychosocial perspective. Rheumatoid arthritis-etiology, consequences and co-morbidities, 2012;9:807-11. DOI:10.5772/26138.
Kapetanovic MC, Lindqvist E, Nilsson JÅ, Geborek P, Saxne T, Eberhardt K. Development of functional impairment and disability in rheumatoid arthritis patients followed for 20 years: relation to disease activity, joint damage, and comorbidity. Arthritis Care Res. 2015; 67(3):340-8.
Jahan S, Humna T, Meer Y, Manzoor S, Tariq A, Khan FM. Association of depression and disability with health related quality of life in patients with rheumatoid arthritis. Foundation Uni J Rehabilit Sci. 2022;2(2):35-39. DOI: https://doi.org/10.33897/fujrs.v2i2.288
Cwirlej-Sozañska A, Sozañski B, Kotarski H, Anna Wilmowska P, Wisniowska-Szurlej A. Psychometric properties and validation of the polish version of the 12- item WHODAS 2.0. BMC Pub Health, 2020;20(1):1-10.
Dadoniene J, Stropuviene S, Venalis A, Boonen A. High work disability rate among rheumatoid arthritis patients in Lithuania. Arthritis Care Res. 2004;51(3):433-9.
Ji J, Zhang L, Zhang Q, Yin R, Fu T, Li L, et al., Functional disability associated with disease and qualityof-life parameters in Chinese patients with rheumatoid arthritis. Health Qual life outcomes, 2017. 15(1): 89. doi: 10.1186/s12955-017-0659-z.
