Primary Malignant Melanoma of The Small Intestine
A Rare Case Reported
Abstract
Primary small intestinal melanoma is a rare malignant neoplasm, for which scarce literature offers limited evidence for optimal management. We present a case of a 60-year-old female with primary melanoma of ileum. She presented with left sided abdominal pain, decreased appetite, and history of diarrhoea for 15 days. She developed absolute constipation during her preoperative investigations, in which CT scan revealed ileoileal intussusception.
She underwent laparotomy for the resection of intussuscepted bowel segment, which revealed a greyish brown mass attached to bowel, later confirmed by histopathology as melanoma. Postoperative detailed clinical investigation revealed no primary cutaneous, hepatic, pulmonary, ocular, or cranial melanotic lesion. Hence, the lesion was classified as primary small bowel melanoma. She was referred to oncologist who started her on adjuvant chemotherapy. The patient expired of cardiopulmonary arrest three months after her diagnosis due to post Chemotherapy side effects.
References
Blecker D, Abraham S, Furth EE, Kochman ML. Melanoma in the gastrointestinal tract. The Am J Gastroenterol. 1999; 94(12):3427-3433.
Sanki A, Scolyer RA, Thompson JF. Surgery for melanoma metastases of the gastrointestinal tract: indications and results. Eur J Surg Oncol. 2009;35(3):313-319.
Yang KM, Kim CW, Kim SW, Lee JL, Yoon YS, Park IJ, et al. Primary malignant melanoma of the small intestine: a report of 2 cases and a review of the literature. Ann Surg Treat Res. 2018;94(5):274-278.
Cheung MC, Perez EA, Molina MA, Jin X, Gutierrez JC, Franceschi D, et al. Defining the role of surgery for primary gastrointestinal tract melanoma. J Gastrointest. 2008;12(4):731- 738. doi: 10.1007/s11605-007-0417-3.
Hadjinicolaou AV, Hadjittofi C, Athanasopoulos PG, Shah R, Ala AA. Primary small bowel melanomas: fact or myth? Ann transl Med. 2016;4(6):113. doi: 10.21037/atm.2016.03.29.
